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Experiments on synthetic models of synaptic vesicles have shed new light on the role of the protein α-synuclein in the central nervous system.

Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.

The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.

The Notch signaling pathway has a central role in the development of the nervous system, and also in the establishment of networks of connections in the adult brain

A protein complex that enables cells to transport substances across their membranes, and that typically consists of four subunits, can also function as two hemicomplexes, each with two subunits.

The nematode worm C. elegans consumes familiar bacterial species more rapidly than it does novel ones, and this preference for familiarity is mediated by a pair of serotonergic neurons.

Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.

The first survey of the complete morphologies of nerve endings in the skin of mice has revealed enormous structural diversity.

A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.

A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.