The nematode worm C. elegans consumes familiar bacterial species more rapidly than it does novel ones, and this preference for familiarity is mediated by a pair of serotonergic neurons.
A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.
J Diao, P Grob, DJ Cipriano, M Kyoung, Y Zhang, S Shah, A Nguyen, M Padolina, A Srivastava, M Vrljic, A Shah, E Nogales, S Chu, AT Brunger