The receptor EBI2 is essential for correctly positioning CD4+ dendritic cells in the spleen so that they can present blood-borne antigens to T cells and thereby provoke an antibody response.
Some of the mutations that occur during influenza evolution can only be tolerated in conjunction with other mutations that increase the stability of a viral protein.
Proteins produced by mast cells modulate the permeability of blood vessels, and may determine whether patients infected with dengue virus develop life-threatening complications.
AL St John, AP Rathore, B Raghavan, M Ng, SN Abraham
A combination of detailed sampling and mathematical modeling suggests that the response of immune cells to reactivation of herpes simplex virus 2 is extremely rapid and effective within microscopic areas of genital skin.
JT Schiffer, D Swan, R Al Sallaq, A Magaret, C Johnston, KE Mark, S Selke, N Ocbamichael, S Kuntz, J Zhu, B Robinson, M Huang, KR Jerome, A Wald, L Corey
Research on humans and dogs reveals that the communities of microorganisms found on the skin, on the tongue and in the intestine are affected differently by age and cohabitation.
SJ Song, C Lauber, EK Costello, CA Lozupone, G Humphrey, D Berg-Lyons, JG Caporaso, D Knights, JC Clemente, S Nakielny, JI Gordon, N Fierer, R Knight
Long-lived intermediate states formed by glycoprotein catalysts are an essential part of the process used by influenza virus particles to infect cells.
T Ivanovic, JL Choi, SP Whelan, AM van Oijen, SC Harrison
Simulations and experiments on systems containing two different populations of microorganisms show that interactions that benefit at least one of the populations can lead to communities with stable compositions, and that strong cooperation between two populations can lead to communities in which both populations are mixed together.