Chronic and excessive inflammation can lead to exhaustion of the supply of hematopoietic stem cells and to myeloid malignancies in mice, mimicking important aspects of the myelodysplastic syndrome found in humans.

A lipid acts to promote the development of nematode worm larvae through activation of an enzyme complex called TORC1.

Identifying and treating those groups of individuals that are most likely to transmit the malaria parasite to mosquitoes could help to control the spread of the disease.

Charybdotoxin, a toxin produced by scorpions, blocks a K+channel by binding in a lock-and-key fashion to the mouth of the channel and presenting a lysine amino group, which serves as a K+mimic in the selectivity filter.

Single absorbed photons trigger adaptational mechanisms that help the retina maintain sensitivity across a wide range of background illumination.

The ability of Manduca moths to recognize changes in the profile of volatile compounds released by plants being attacked by Manduca caterpillars allows them to lay their eggs on plants that are less likely to be attacked by insects and other predators, and to avoid competing against other caterpillars of the same species for resources.

The receptor EBI2 is essential for correctly positioning CD4+ dendritic cells in the spleen so that they can present blood-borne antigens to T cells and thereby provoke an antibody response.

Sites at which mitochondria contact the endoplasmic reticulum co-localize the replication of mitochondria and their DNA to help ensure that DNA is distributed appropriately between the newly formed organelles in cells.

Some of the mutations that occur during influenza evolution can only be tolerated in conjunction with other mutations that increase the stability of a viral protein.

A protein called PVRL4 has a central role in a number of cancers that originate in epithelial tissue, and anti-PVRL4 antibodies could be used to treat some of these cancers.