Structural Biology and Molecular Biophysics

Latest articles

1. 1. Structural Biology and Molecular Biophysics

   N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine

   Chuchu Wang, Chunyu Zhao ... Cong Liu
2. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

   Sandeep K. Ravala, Sendi Rafael Adame-Garcia ... John J. G. Tesmer
3. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX

   Isabelle Petit-Hartlein, Annelise Vermot ... Franck Fieschi

   Detailed molecular characterization of a constitutively active bacterial NADPH oxidase (NOX) provides clues to the activation mechanism required to trigger electron transfer and reactive oxygen species (ROS) production in tightly regulated eukaryotic NOX.
4. 1. Structural Biology and Molecular Biophysics

   Dependence of Nucleosome Mechanical Stability on DNA Mismatches

   Thuy T. M. Ngo, Bailey Liu ... Taekjip Ha
5. 1. Structural Biology and Molecular Biophysics

   Structural insights in the GTP-driven monomerization and activation of a bacterial LRRK2 homologue using allosteric nanobodies

   Christian Galicia, Giambattista Guaitoli ... Wim Versées
6. 1. Structural Biology and Molecular Biophysics
   2. Developmental Biology

   Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

   Arne Elofsson, Ling Han ... Luca Jovine
7. 1. Structural Biology and Molecular Biophysics

   The substrate-binding domains of the osmoregulatory ABC importer OpuA transiently interact

   Marco van den Noort, Panagiotis Drougkas ... Bert Poolman
8. 1. Structural Biology and Molecular Biophysics

   LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction

   Colin H Peters, Rohit K Singh ... John R Bankston
9. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates

   Andrew P. Latham, Longchen Zhu ... Bin Zhang
10. 1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Effect of α-tubulin acetylation on the doublet microtubule structure

    Shun Kai Yang, Shintaroh Kubo ... Khanh Huy Bui

    Cryo-EM studies of doublet microtubules from wild-type and acetylation mutants suggest that acetylation of K40 affects the lateral rotational angle between protofilaments, leading to changes in the structure and stability.