Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila CNS

    Sanjay Kumar Sukumar, Vimala Antonydhason ... Ruth H. Palmer
    1. Developmental Biology

    FMNL2 regulates actin for ER and mitochondria distribution in oocyte meiosis

    Meng-Hao Pan, Zhen-Nan Pan ... Shao-Chen Sun
    1. Developmental Biology

    SMAD4 promotes somatic-germline contact during murine oocyte growth

    Sofia Granados-Aparici, Qin Yang, Hugh Clarke
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

    Arne Elofsson, Ling Han ... Luca Jovine
    AlphaFold-Multimer was used to investigate extracellular protein interactions involved in mammalian egg-sperm recognition, suggesting a putative pentameric complex that includes TMEM81, a sperm protein not previously involved in gamete recognition.
    1. Developmental Biology

    Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

    Amandine Jarysta, Abigail LD Tadenev ... Basile Tarchini
    Sensory hair cells in the inner ear use inhibitory G proteins with different regulators at different stages of development to break symmetry, adopt a proper orientation, and grow stereocilia.
    1. Computational and Systems Biology
    2. Developmental Biology

    A logic-incorporated gene regulatory network deciphers principles in cell fate decisions

    Gang Xue, Xiaoyi Zhang ... Zhiyuan Li
    A top-down model-guided framework unveils the role of regulatory logics underlying gene regulatory networks in cell fate decisions.
    1. Developmental Biology
    2. Evolutionary Biology

    The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition

    Zhuqing Wang, Yue Wang ... Wei Yan
    The rapidly evolving X-linked MIR-506 family miRNAs function to enhance sperm competitiveness and male reproductive fitness in mice.
    1. Developmental Biology

    Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

    Edgar M Pera, Josefine Nilsson-De Moura ... Ivana Milas
    An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    N-Terminus of Drosophila Melanogaster MSL1 Is Critical for Dosage Compensation

    Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko

Highlights

    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Claude Desplan
    New York University, United States
  4. See more editors