Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Clonotypic tracing of SARS-CoV-2–responsive T cells reveals vaccination-induced dominant Tfh clonotypes, not pre-existing T cells, associated with sustained humoral response, and can serve as an index of antigen-specific antibody longevity.
Collaborative hunting, characterized by the division of roles among predators, has emerged within a group of artificial agents through deep reinforcement learning.
Mohammad Alfatah, Jolyn Jia Jia Lim ... Frank Eisenhaber
Revealing YBR238C's involvement in the TORC1–mitochondria feedback loop deepens our understanding of aging biology, emphasizing the TOMITO concept as a crucial mechanism in cellular aging regulation.
Empirical experiments and computational modeling reveal a stochastic world model on gravity for stability inference that represents gravity’s vertical direction as a Gaussian distribution.
Nicholas James Ose, Paul Campitelli ... Sefika Banu Ozkan
Insights from integrating evolutionary predictions and protein dynamics unveil how specific mutations in the SARS-CoV-2 spike protein epistatically interact in order to influence spike protein interaction with human cells, potentially altering the virus's infectivity and immune evasion capabilities.
Psychophysical measurement and computational modeling show that sensory information cannot contribute directly to a cognitive judgment, but must first be integrated into resource-limited working memory.
Purine recycling deficiency triggers metabolic and neurological defects reminiscent of Lesch–Nyhan disease in Drosophila, paving the way for studying this disorder and carrying out drug screening in an invertebrate organism.
