Figure 1—figure supplement 3. | Passive and active DNA methylation and the interplay with genetic variation in gene regulation

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Passive and active DNA methylation and the interplay with genetic variation in gene regulation

Figure 1—figure supplement 3.

Affiliation details

University of Geneva Medical School, Switzerland; Institute of Genetics and Genomics in Geneva, Switzerland; Swiss Institute of Bioinformatics, Switzerland; Stanford University, United States
Figure 1—figure supplement 3.
Download figureOpen in new tabFigure 1—figure supplement 3. Covariates for which expression data was corrected.

(A) Histogram of mean GC content per library before removing outliers. (B) Histogram of insert size mode per library before removing outliers. The two samples in the extreme left were considered technical outliers and were removed. (C)–(F) p value distributions, with π1 indicated in each plot, of the linear regression effects of the four covariates we later corrected for on scaled exon levels.

DOI: http://dx.doi.org/10.7554/eLife.00523.006