Figure 4—figure supplement 2. | Passive and active DNA methylation and the interplay with genetic variation in gene regulation

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Passive and active DNA methylation and the interplay with genetic variation in gene regulation

Figure 4—figure supplement 2.

Affiliation details

University of Geneva Medical School, Switzerland; Institute of Genetics and Genomics in Geneva, Switzerland; Swiss Institute of Bioinformatics, Switzerland; Stanford University, United States
Figure 4—figure supplement 2.
Download figureOpen in new tabFigure 4—figure supplement 2. Associations between TF abundance and DNA methylation at their target binding sites.

Observed (left panels) and expected (right panels) p value distributions of spearman correlations between transcription factor expression levels and DNA methylation levels of eQTMs at their binding sites (see ‘Materials and methods’) in fibroblasts (F), LCLs (L) and T-cells (T). π1 statistic, reflecting the fraction of true positives, is indicated on top of each p value distribution.

DOI: http://dx.doi.org/10.7554/eLife.00523.021