Figure 5. | Expanding the olfactory code by in silico decoding of odor-receptor chemical space

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Expanding the olfactory code by in silico decoding of odor-receptor chemical space

Figure 5.

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University of California, Riverside, United States
Figure 5.
Download figureOpen in new tabFigure 5. Analysis of predicted natural odor sources and cross activation.

(A) (Left) The numbers of compounds present in the collected volatile library according to source. (Right) The numbers and sources of predicted ligands for the 19 Drosophila odor receptors/neurons within the top 500 predicted compounds. (B) Comparison of plots for percentage of receptors that are: (top left) activated by percentage of known odors from training set (Hallem and Carlson, 2006); (bottom left) predicted to be activated by Natural compound library; (top right) predicted to be activated from >240K library; and (bottom right) activated by ligands for 10 shared Ors in this study vs activated by comparable actives previously tested (Hallem and Carlson, 2006).

DOI: http://dx.doi.org/10.7554/eLife.01120.011