Opioids stop breathing during overdose by silencing two small brain sites, with just 140 neurons in the breathing rhythm generator exerting the key effect.

Cancer-directed treatment using Tumor-Treating Fields spatially modulates the tumor microenvironment at the cellular and molecular levels, decreasing nanotube-based cellular networks of communication while creating a microenvironment more susceptible to immunotherapeutic strategies.

20 emerging issues in bioengineering that will have profound impacts on society have been identified.

A control system model of cerebellar patients' movements provides insight into the cerebellum's role in reaching and informs a virtual reality intervention to improve patient reaches.

Cellular and chemogenetic approaches identify a novel mode of chemotransduction involving regulation of basal breathing by CO₂/H+-dependent disinhibition.

Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.

A group of neurons in the medulla expressing the tachykinin precursor 1 promote rhythmic breathing, but also elicit substantial motor behaviors, suggesting a dual role for these neurons in the medulla.

The neuromodulator substance P enhances mechanisms of recurrent excitation between breaths to control breathing frequency and stability.

Standing genetic variation for disease resistance may be continuously lost during recurring warm water episodes because of widespread susceptibility of disease-resistant genotypes to bleaching and the independence between these two traits.

The postinspiratory complex acts as an interface between the swallow pattern generator and the preBötzinger complex to coordinate swallow and breathing.