17,629 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

    Amrita Rai, Anastasia Oprisko ... Matthias P Müller
    A human three-helix Rab-binding domain can potentially bind to two Rab proteins simultaneously with different affinities at binding sites generated by gene duplication.
    1. Neuroscience

    Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

    Yoshinori Aso, Robert P Ray ... Gerald M Rubin
    The interplay of nitric oxide and dopamine specialize one memory unit in a fly brain in predicting the value of odors based only on recent experience.
    1. Neuroscience

    Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex

    Rajnish P Rao, Falk Mielke ... Michael Brecht
    Snout-to-snout contact modulates the response of rat auditory cortex to calls from other animals, indicating that the multisensory nature of social interaction is directly represented in the rat brain.
    1. Genetics and Genomics

    Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

    Prithvi Raj, Ekta Rai ... Edward K Wakeland
    Genetic variations that underlie common autoimmune disease genes are predominantly regulatory and modify the expression of multiple genes within the HLA gene complex and throughout the immune system.
    1. Physics of Living Systems

    Glycan processing in the Golgi as optimal information coding that constrains cisternal number and enzyme specificity

    Alkesh Yadav, Quentin Vagne ... Madan Rao
    A mathematical model of glycosylation in the Golgi apparatus to investigate how the fidelity of synthesising a complex glycan distribution at the plasma membrane depends on parameters such as the number of Golgi cisternae or enzyme specificity.
    1. Stem Cells and Regenerative Medicine
    2. Immunology and Inflammation

    MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

    Jimmy L Zhao, Dinesh S Rao ... David Baltimore
    Chronic and excessive inflammation can lead to exhaustion of the supply of hematopoietic stem cells and to myeloid malignancies in mice, mimicking important aspects of the myelodysplastic syndrome found in humans.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community

    Kevin D'hoe, Stefan Vet ... Jeroen Raes
    Human gut bacteria alter their metabolism in response to each other's presence, which causes their community dynamics to deviate from predictions that are based on mono-culture data.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Consistent global structures of complex RNA states through multidimensional chemical mapping

    Clarence Yu Cheng, Fang-Chieh Chou ... Rhiju Das
    A multidimensional chemical mapping strategy enables confident determination of the structures of non-coding RNAs at 1-nm resolution, including previously intractable riboswitch and human regulon states.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA

    Hemant N Goswami, Jay Rai ... Hong Li
    Three-dimensional structure of CRISPR Cas7-11 shed light on protein evolution and guide development of biotechnology for RNA manipulations in cells.
  1. Meta-Research: Tracking the popularity and outcomes of all bioRxiv preprints

    Richard J Abdill, Ran Blekhman
    Data are reported for the monthly number of uploads to and downloads from bioRxiv, and for the number of preprints that are later published in peer-reviewed journals.

Refine your results by:

Type
Research categories