Mary K Thompson, Maria F Rojas-Duran ... Wendy V Gilbert
Asc1/RACK1 promotes the translation of mRNAs associated with the translational closed loop complex, which have short open reading frames and encode proteins required for core metabolic processes.
Michael Zavortink, Lauren N Rutt ... Olivia S Rissland
In fruit flies, maternally deposited RNA-binding proteins are removed during the maternal-to-zygotic transition via a mechanism of translational upregulation of Kondo, the key E2 enzyme, at egg activation.
Markus Terrey, Scott I Adamson ... Susan L Ackerman
Disruption of quality control pathways that function at distinct steps to mitigate errors in translation evoke similar cellular responses and pathologies.
Ribosome profiling has bridged the knowledge gap between transcription and translation during malaria blood stage development and provided a comprehensive gene expression resource for this parasite.
Magdalena M Maslon, Sara R Heras ... Javier F Cáceres
Identifying the translational targets of the shuttling protein, SRSF1, reveals that it is needed for normal cell division, and suggests that it couples pre-mRNA splicing and translation.
Mohsen Jamali, Jerome Carriot ... Kathleen E Cullen
Through different coding strategies, irregular and regular otolith afferents preferentially encode translational self-motion and changes in static head orientation relative to gravity.
Without ribosome recycling factor, ribosomes in Escherichia coli accumulate in 3'-UTRs and queue upstream of stop codons, but no effects were observed on the translational coupling of neighboring genes.
The deletion of Ddx6 results in the translational upregulation, but not transcript stabilization, of microRNA targets in embryonic stem cells while largely phenocopying the overall impact of global microRNA loss.