Browse our latest Computational and Systems Biology articles

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    1. Cell Biology
    2. Computational and Systems Biology

    Neural network emulation of the human ventricular cardiomyocyte action potential for more efficient computations in pharmacological studies

    Thomas Grandits, Christoph M Augustin ... Alexander Jung
    Neural networks can emulate normal and abnormal human ventricular action potentials accurately and potentially much faster than regular simulations paving the way for more efficient quantitative systems pharmacology studies.
    1. Computational and Systems Biology
    2. Cancer Biology

    Optimal transport for automatic alignment of untargeted metabolomic data

    Marie Breeur, George Stepaniants ... Vivian Viallon
    1. Computational and Systems Biology
    2. Neuroscience

    Disrupting abnormal neuronal oscillations with adaptive delayed feedback control

    Domingos Leite de Castro, Miguel Aroso ... Paulo Aguiar
    Adaptive delayed feedback control is presented as a new real-time, closed-loop control algorithm for neurostimulation which can disrupt oscillations and reduce network synchrony in neuronal populations.
    1. Cancer Biology
    2. Computational and Systems Biology

    Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction

    Sara Latini, Veronica Venafra ... Francesca Sacco
    Acute myeloid leukemia-specific predictive logic models reveal new therapeutic targets involved in cancer resistance mechanisms paving the way for personalized precision medicine.