Browse our latest Computational and Systems Biology articles

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    1. Computational and Systems Biology
    2. Cancer Biology

    Optimal transport for automatic alignment of untargeted metabolomic data

    Marie Breeur, George Stepaniants ... Vivian Viallon
    1. Computational and Systems Biology
    2. Neuroscience

    Disrupting abnormal neuronal oscillations with adaptive delayed feedback control

    Domingos Leite de Castro, Miguel Aroso ... Paulo Aguiar
    Adaptive delayed feedback control is presented as a new real-time, closed-loop control algorithm for neurostimulation which can disrupt oscillations and reduce network synchrony in neuronal populations.
    1. Cancer Biology
    2. Computational and Systems Biology

    Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction

    Sara Latini, Veronica Venafra ... Francesca Sacco
    Acute myeloid leukemia-specific predictive logic models reveal new therapeutic targets involved in cancer resistance mechanisms paving the way for personalized precision medicine.
    1. Computational and Systems Biology

    Protein language model-embedded geometric graphs power inter-protein contact prediction

    Yunda Si, Chengfei Yan
    Integrating multiple protein language models using protein geometric graphs can dramatically improve the model performance for predicting the contacting residue pairs between interacting proteins.
    1. Cell Biology
    2. Computational and Systems Biology

    circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

    Trine Line Hauge Okholm, Andreas Bjerregaard Kamstrup ... Christian Kroun Damgaard