Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health

    Modeling resource allocation strategies for insecticide-treated bed nets to achieve malaria eradication

    Nora Schmit, Hillary M Topazian ... Azra C Ghani
    The optimal allocation strategy prioritizes funding to high-transmission settings in sub-Saharan Africa, but highlights a trade-off between reducing clinical malaria burden and reducing the global population at risk of malaria.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

    Raman Sharma, Chao Chen ... Panayota Bird
    We are writing to comment on the article by Watson et al., 2022 about the antimalarial drug tafenoquine.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Response to comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

    James A Watson, Robert J Commons ... Nicholas J White
    We are writing to respond to comment by Sharma et al, 2024 on our article about the antimalarial drug tafenoquine.
    1. Epidemiology and Global Health
    2. Medicine

    Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers

    Sasithon Pukrittayakamee, Podjanee Jittamala ... Nicholas J White
    A full radical curative dose of primaquine can be given to fully glucose-6-phosphate dehydrogenase-deficient males safely using an ascending dose regimen.
    1. Epidemiology and Global Health
    2. Computational and Systems Biology

    Reliance on self-reports and estimated food composition data in nutrition research introduces significant bias that can only be addressed with biomarkers

    Javier I. Ottaviani, Virag Sagi-Kiss ... Gunter G. C. Kuhnle
    1. Epidemiology and Global Health

    Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy

    Silvia de Sanjosé, Rebecca B Perkins ... Mark Schiffman
    The PAVE strategy aims to provide a cost-effective, high quality ‘Screen-Triage-Treat’ approach for cervical cancer screening to save many lives.
    1. Genetics and Genomics
    2. Epidemiology and Global Health

    Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry

    Wei Q. Deng, Nathan Cawte ... Sonia S. Anand
    1. Epidemiology and Global Health

    Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

    Kathryn E. Tiedje, Qi Zhan ... Karen P. Day
    1. Cancer Biology
    2. Epidemiology and Global Health

    Identifying metabolic features of colorectal cancer liability using Mendelian randomization

    Caroline Bull, Emma Hazelwood ... Emma E Vincent
    Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating the contribution of subclinical tuberculosis disease to transmission: An individual patient data analysis from prevalence surveys

    Jon C Emery, Peter J Dodd ... Rein MGJ Houben
    Data analysis and mathematical modelling suggest that subclinical tuberculosis contributes substantially to transmission and needs to be diagnosed and treated for effective progress towards tuberculosis elimination.
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