Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

   Ziyu Wen, Pingchao Li ... Caijun Sun
2. 1. Immunology and Inflammation
   2. Computational and Systems Biology

   Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

   Jan Stuchly, David Novak ... Tomas Kalina
3. 1. Immunology and Inflammation

   RAG1 and RAG2 Non-core Regions Are Implicated in Leukemogenesis and Off-target V(D)J Recombination in BCR-ABL1-driven B-cell Lineage Lym-phoblastic Leukemia

   Xiaozhuo Yu, Wen Zhou ... Yanhong Ji
4. 1. Immunology and Inflammation

   Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt

   Phillip A Erice, Xinyan Huang ... Antony Rodriguez

   Mirlet7 functions as a molecular brake of CD8⁺IL17a⁺ T cells (Tc17) inflammation and chronic obstructive pulmonary disease via direct regulation RAR-related orphan receptor gamma t (RORγt).
5. 1. Immunology and Inflammation

   Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

   Xiuyuan Lu, Hiroki Hayashi ... Sho Yamasaki

   Clonotypic tracing of SARS-CoV-2–responsive T cells reveals vaccination-induced dominant Tfh clonotypes, not pre-existing T cells, associated with sustained humoral response, and can serve as an index of antigen-specific antibody longevity.
6. 1. Immunology and Inflammation

   CD81⁺ fibroblasts, a unique subpopulation with accelerated cellular senescence, exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

   Liangliang Fu, Chenghu Yin ... Haibin Xia
7. 1. Medicine
   2. Immunology and Inflammation

   Anti-inflammatory therapy with nebulised dornase alfa for severe COVID-19 pneumonia

   Joanna C. Porter, Jamie Inshaw ... Venizelos Papayannopoulos
8. 1. Immunology and Inflammation
   2. Computational and Systems Biology

   Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions

   Pengfei Zhang, Seojin Bang ... Heewook Lee
9. 1. Immunology and Inflammation

   Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity

   Leen Farhat-Younis, Manho Na ... Yaron Carmi
10. 1. Immunology and Inflammation

    Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4⁺ T cells through STAT1-related epigenetic mechanisms

    Jie Zhang, Hui Tang ... Yu Zhang