Vocal learning in bats

Latest research

1. 1. Immunology and Inflammation

   CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

   Xiaoyu Meng, Yezhang Zhu ... Lie Wang

   CXXC1 is a pivotal epigenetic regulator that ensures T_reg homeostasis and suppressive function by interacting with FOXP3 to modulate H3K4me3 deposition at key signature genes.
2. 1. Developmental Biology

   Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation

   Mehmet Mahsum Kaplan, Erika Hudacova ... Ondrej Machon

   Meis2 transcription factor instructs the mesenchyme to initiate whisker formation in the epithelium.
3. 1. Cell Biology

   Small-molecule activation of TFEB alleviates Niemann–Pick disease type C via promoting lysosomal exocytosis and biogenesis

   Kaili Du, Hongyu Chen ... Dan Li

   Small-molecule agonists of transcription factor EB alleviate Niemann–Pick disease type C via promoting lysosomal function.
4. 1. Microbiology and Infectious Disease

   Linalool combats Saprolegnia parasitica infections through direct killing of microbes and modulation of host immune system

   Tao Tang, Weiming Zhong ... Zhipeng Gao

   Linalool demonstrates dual antimicrobial and immunomodulatory actions against Saprolegnia parasitica.
5. 1. Neuroscience
   2. Physics of Living Systems

   Annihilation of action potentials induces electrical coupling between neurons

   Moritz Schloetter, Georg U Maret, Christoph J Kleineidam

   Action potentials of neurons expel a charge when they reach the axon terminal, and classical electrodynamics predict the resulting electric fields and its influence to other neurons by ephaptic coupling.
6. 1. Ecology
   2. Evolutionary Biology

   Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene

   Vendula Bohlen Šlechtová, Tomáš Dvořák ... Joerg Bohlen

   The first comprehensive reconstruction of the evolutionary history of freshwater animals, on example of family Nemacheilidae, across Eurasia with the identification of the main tectonic, geological, and climatic factors influencing it has been described.
7. 1. Plant Biology

   The rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

   Hanbin Bao, Yanan Wang ... Yangrong Cao

   The rhizobial effector NopT and two Nod factor receptors of Lotus japonicus, NFR1 and NFR5, mutually interact to precisely regulate rhizobial symbiosis.
8. 1. Cell Biology

   Stratification of enterochromaffin cells by single-cell expression analysis

   Yan Song, Linda J Fothergill ... Gene W Yeo

   Molecularly defined serotonin (enterochromaffin) cells of the gut lining were distinguished by single-cell expression analysis, in situ hybridization, and immunohistochemistry into 14 topographically organized clusters, with features implying that they are functionally distinct classes of serotonin cells.
9. 1. Biochemistry and Chemical Biology
   2. Genetics and Genomics

   Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid

   Josep Fita-Torró, José Luis Garrido-Huarte ... Markus Proft
10. 1. Genetics and Genomics
    2. Cancer Biology

    Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity

    Hirokazu Kimura, Kamel Lahouel ... Nicholas J Roberts