1. Neuroscience

The topography of frequency and time representation in primate auditory cortices

  1. Simon Baumann  Is a corresponding author
  2. Olivier Joly
  3. Adrian Rees
  4. Christopher I Petkov
  5. Li Sun
  6. Alexander Thiele
  7. Timothy D Griffiths
  1. Newcastle University, United Kingdom
  2. University of Oxford, United Kingdom
https://doi.org/10.7554/eLife.03256
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  1. Simon Baumann
  2. Olivier Joly
  3. Adrian Rees
  4. Christopher I Petkov
  5. Li Sun
  6. Alexander Thiele
  7. Timothy D Griffiths
(2015)
The topography of frequency and time representation in primate auditory cortices
eLife 4:e03256.
https://doi.org/10.7554/eLife.03256
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Abstract

Natural sounds can be characterised by their spectral content and temporal modulation, but how the brain is organized to analyse these two critical sound dimensions remains uncertain. Using functional magnetic resonance imaging, we demonstrate a topographical representation of amplitude modulation rate in the auditory cortex of awake macaques. The representation of this temporal dimension is organized in approximately concentric bands of equal rates across the superior temporal plane in both hemispheres, progressing from high rates in the posterior core to low rates in the anterior core and lateral belt cortex. In A1 the resulting gradient of modulation rate runs approximately perpendicular to the axis of the tonotopic gradient, suggesting an orthogonal organisation of spectral and temporal sound dimensions. In auditory belt areas this relationship is more complex. The data suggest a continuous representation of modulation rate across several physiological areas, in contradistinction to a separate representation of frequency within each area.

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Author details

  1. Simon Baumann

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    For correspondence
    simon.baumann@ncl.ac.uk
    Competing interests
    The authors declare that no competing interests exist.

  2. Olivier Joly

    MRC Cognition and Brain Sciences Unit, Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

  3. Adrian Rees

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

  4. Christopher I Petkov

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

  5. Li Sun

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

  6. Alexander Thiele

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

  7. Timothy D Griffiths

    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.

Reviewing Editor

  1. Eve Marder, Brandeis University, United States

Ethics

Animal experimentation: All experiments were carried out in accordance with the UK, Animals (Scientific Procedures) Act (1986), European Communities Council Directive 1986 (86/609/EEC) and the US National Institutes of Health Guidelines for the Care and Use of Animals for Experimental Procedures, and were performed with great care to ensure the well-being of the animals.

Version history

  1. Received: May 4, 2014
  2. Accepted: January 14, 2015
  3. Accepted Manuscript published: January 15, 2015 (version 1)
  4. Version of Record published: April 16, 2015 (version 2)

Copyright

© 2015, Baumann et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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  1. Simon Baumann
  2. Olivier Joly
  3. Adrian Rees
  4. Christopher I Petkov
  5. Li Sun
  6. Alexander Thiele
  7. Timothy D Griffiths
(2015)
The topography of frequency and time representation in primate auditory cortices
eLife 4:e03256.
https://doi.org/10.7554/eLife.03256

Share this article

https://doi.org/10.7554/eLife.03256

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